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GREEN tea is said
to have near-miraculous curing powers, and new research now
boosts the theory that the beverage may someday play a role as
an AIDS fighter.
Experts caution that the results of a newly released
laboratory study from Japan are preliminary and may not mean
anything outside of test tubes. But the research does suggest
heavy doses of green tea could prevent the AIDS virus from
infecting the body's immune cells.
"It really hasn't been proven yet, but it's something that
ought to be pursued," says Dr. William T. Shearer, a professor
of pediatrics and immunology at Baylor College of Medicine and
author of a commentary on the findings.
Green tea, a popular drink in Asia, has been called a
potential treatment for stomach disorders, cancer and
bacterial infections, among many other ailments from high
cholesterol to tooth decay. Scientists suspect the ingredient
behind its apparent powers is a compound known as
epigallocatechin-3-gallate, or EGCG.
Researchers at the University of Tokyo examined the effects of
EGCG on the process of HIV infection. They report their
findings in the November issue of the Journal of Allergy and
Clinical Immunology.
The researchers found the substance blocked the AIDS virus
from latching onto the T-cells. When HIV successfully attacks
these "spark plugs" of the immune system, the body loses its
ability to fight off infection and becomes susceptible to
numerous potentially deadly illnesses, Shearer says.
This is promising because existing AIDS drugs have limited
powers, Shearer says. They target cells that have already been
infected, but don't stop the infection of cells in the first
place. "There are always new infections that are taking place
every day, every hour, every minute," he says. "A drug that
could prevent new infections would be a wonderful adjunct
medication."
So, should AIDS patients rush out to the health-food store to
stock up on green tea? Shearer and other experts don't think
so. "Nobody's ready to say this proves that one ought to drink
gallons of green tea every day," Shearer says.
For one, it may take quite a lot of green tea each day to have
any impact. Research has suggested that two cups of green tea
a day won't take patients anywhere near the blood level they
may need, Shearer says.
For another thing, researchers haven't tried their theories on
humans. Also, it's not clear whether too much green tea in the
bloodstream could be toxic, says Frank Edward Myers III, an
AIDS expert and epidemiologist at Scripps Mercy Hospital in
San Diego.
Even so, researchers are hopeful about harnessing the powers
of green tea into a drug. "It's very exciting," says Dr.
Christopher Randolph, an associate clinical professor of
allergy and immunology at Yale University, "but I'd be
cautious about saying something may be applicable tomorrow."
Myers also urges caution. "Early results like these can often
be encouraging but later found to be dead ends, not useful in
developing treatments," he says. "A lot more testing needs
done before this can be applied in patient care."
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